Sorting nexins (SNX) are proteins which enhance membrane association via their lipid-binding PX domain or via protein-protein association. The PX domain contains a phospholipid-binding motif.
3D structures of sorting nexin
Updated on 04-July-2013
SNX-1
2i4k – hSNX PX domain - NMR
SNX-3
1ocs – ySNX PX domain – yeast
1ocu – ySNX PX domain + phosphatidylinositol-3-phosphate
2yps – hSNX PX domain
SNX-5
3hpb, 3hpc – rSNX PX domain – rat
SNX-7
3iq2 – hSNX PX domain
SNX-9
2enm – SNX SH3 domain – mouse - NMR
2rai, 2raj, 2rak, 3dyt, 3dyu – hSNX PX-BAR domain
3lge – SNX residues 152-182 + aldolase – rabbit
SNX-11
4ikb, 4ikd – hSNX PX domain
SNX-12
2csk – hSNX PX domain
SNX-14
4bgj – hSNX PX domain
SNX-17
3fog, 3lui – hSNX PX domain
4gxb – hSNX FERM domain + P-selectin NPXY motif
SNX-22
2ett – hSNX PX domain - NMR
SNX-24
4az9 – hSNX PX domain
SNX-27
3qdo, 3qe1 – rSNX PDZ domain/GIRK3 C terminal
3qgl – rSNX PDZ domain + GIRK3 C terminal
4has – hSNX PX domain
SNX-33
4akv – hSNX PH-BAR domain
