4h24
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_4h24| PDB=4h24 | SCENE= }} | {{STRUCTURE_4h24| PDB=4h24 | SCENE= }} | ||
===Cytochrome P411BM3-CIS cyclopropanation catalyst=== | ===Cytochrome P411BM3-CIS cyclopropanation catalyst=== | ||
| + | {{ABSTRACT_PUBMED_23792734}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. | [[4h24]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H24 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023792734</ref><references group="xtra"/><references/> | ||
[[Category: Bacillus megaterium]] | [[Category: Bacillus megaterium]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
Revision as of 14:22, 10 July 2013
Contents |
Cytochrome P411BM3-CIS cyclopropanation catalyst
Template:ABSTRACT PUBMED 23792734
Function
[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.
About this Structure
4h24 is a 4 chain structure with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.
Reference
- Coelho PS, Wang ZJ, Ener ME, Baril SA, Kannan A, Arnold FH, Brustad EM. A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo. Nat Chem Biol. 2013 Jun 23. doi: 10.1038/nchembio.1278. PMID:23792734 doi:10.1038/nchembio.1278
