3sir
From Proteopedia
(Difference between revisions)
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- | [[Image:3sir.png|left|200px]] | ||
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{{STRUCTURE_3sir| PDB=3sir | SCENE= }} | {{STRUCTURE_3sir| PDB=3sir | SCENE= }} | ||
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===Crystal Structure of drICE=== | ===Crystal Structure of drICE=== | ||
+ | {{ABSTRACT_PUBMED_21811237}} | ||
+ | ==Function== | ||
+ | [[http://www.uniprot.org/uniprot/ICE_DROME ICE_DROME]] Involved in the activation cascade of caspases responsible for apoptosis execution. Acts downstream of rpr. Cleaves baculovirus p35 and lamin DmO in vitro. | ||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Caspase|Caspase]] | *[[Caspase|Caspase]] | ||
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+ | ==Reference== | ||
+ | <ref group="xtra">PMID:021811237</ref><references group="xtra"/><references/> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Li, X.]] | [[Category: Li, X.]] |
Revision as of 14:35, 10 July 2013
Contents |
Crystal Structure of drICE
Template:ABSTRACT PUBMED 21811237
Function
[ICE_DROME] Involved in the activation cascade of caspases responsible for apoptosis execution. Acts downstream of rpr. Cleaves baculovirus p35 and lamin DmO in vitro.
About this Structure
3sir is a 4 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
See Also
Reference
- Li X, Wang J, Shi Y. Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE. Nat Commun. 2011 Aug 2;2:408. doi: 10.1038/ncomms1418. PMID:21811237 doi:10.1038/ncomms1418