This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2ieh
From Proteopedia
(New page: 200px<br /> <applet load="2ieh" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ieh, resolution 2.7Å" /> '''Crystal structure of...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2ieh.gif|left|200px]]<br /> | + | [[Image:2ieh.gif|left|200px]]<br /><applet load="2ieh" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2ieh" size=" | + | |
caption="2ieh, resolution 2.7Å" /> | caption="2ieh, resolution 2.7Å" /> | ||
'''Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer'''<br /> | '''Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 2IEH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MG, K, CL, ADP, MOY and PG4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Plus-end-directed_kinesin_ATPase Plus-end-directed kinesin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.4 3.6.4.4] Full crystallographic information is available from [http:// | + | 2IEH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=ADP:'>ADP</scene>, <scene name='pdbligand=MOY:'>MOY</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Plus-end-directed_kinesin_ATPase Plus-end-directed kinesin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.4 3.6.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IEH OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Plus-end-directed kinesin ATPase]] | [[Category: Plus-end-directed kinesin ATPase]] | ||
| Line 20: | Line 19: | ||
[[Category: flanked by three alpha-helices on each side]] | [[Category: flanked by three alpha-helices on each side]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:51:49 2008'' |
Revision as of 15:51, 21 February 2008
|
Crystal structure of human kinesin Eg5 in complex with (R)-mon97, a new monastrol-based inhibitor that binds as (R)-enantiomer
About this Structure
2IEH is a Single protein structure of sequence from Homo sapiens with , , , , and as ligands. Active as Plus-end-directed kinesin ATPase, with EC number 3.6.4.4 Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 17:51:49 2008
