2if4
From Proteopedia
(New page: 200px<br /><applet load="2if4" size="450" color="white" frame="true" align="right" spinBox="true" caption="2if4, resolution 2.85Å" /> '''Crystal structure of...) |
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| - | [[Image:2if4.gif|left|200px]]<br /><applet load="2if4" size=" | + | [[Image:2if4.gif|left|200px]]<br /><applet load="2if4" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2if4, resolution 2.85Å" /> | caption="2if4, resolution 2.85Å" /> | ||
'''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana'''<br /> | '''Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana'''<br /> | ||
==Overview== | ==Overview== | ||
| - | FKBP42 is a membrane-anchored immunophilin playing a critical role in | + | FKBP42 is a membrane-anchored immunophilin playing a critical role in morphogenesis and development of higher plants. We present the X-ray structure of the cytoplasmic portion of FKBP42 comprising both the FKBP-like domain and the TPR domain at 2.85 A resolution. The data shed light on the probable binding modes of key interaction partners, including HSP90 and two classes of ABC transporters. The resulting models provide a structural background for further investigation of the unique biological properties of this protein. |
==About this Structure== | ==About this Structure== | ||
| - | 2IF4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http:// | + | 2IF4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IF4 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Eckhoff, A.]] | [[Category: Eckhoff, A.]] | ||
[[Category: Granzin, J.]] | [[Category: Granzin, J.]] | ||
| - | [[Category: Weiergraeber, O | + | [[Category: Weiergraeber, O H.]] |
[[Category: alpha]] | [[Category: alpha]] | ||
[[Category: alpha-beta]] | [[Category: alpha-beta]] | ||
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[[Category: tpr-like]] | [[Category: tpr-like]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:51:58 2008'' |
Revision as of 15:51, 21 February 2008
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Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana
Overview
FKBP42 is a membrane-anchored immunophilin playing a critical role in morphogenesis and development of higher plants. We present the X-ray structure of the cytoplasmic portion of FKBP42 comprising both the FKBP-like domain and the TPR domain at 2.85 A resolution. The data shed light on the probable binding modes of key interaction partners, including HSP90 and two classes of ABC transporters. The resulting models provide a structural background for further investigation of the unique biological properties of this protein.
About this Structure
2IF4 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
Crystal structure of a multi-domain immunophilin from Arabidopsis thaliana: a paradigm for regulation of plant ABC transporters., Granzin J, Eckhoff A, Weiergraber OH, J Mol Biol. 2006 Dec 8;364(4):799-809. Epub 2006 Sep 26. PMID:17045295
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