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4kw5

From Proteopedia

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m (Protected "4kw5" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4kw5| PDB=4kw5 | SCENE= }}
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===M. tuberculosis DprE1 in complex with inhibitor TCA1===
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{{ABSTRACT_PUBMED_23776209}}
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The entry 4kw5 is ON HOLD
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==About this Structure==
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[[4kw5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KW5 OCA].
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Authors: Batt, S.M., Besra, G.S., Futterer, K.
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==Reference==
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<ref group="xtra">PMID:023776209</ref><references group="xtra"/><references/>
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Description: M. tuberculosis DprE1 in complex with inhibitor TCA1
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[[Category: Decaprenylphospho-beta-D-ribofuranose 2-oxidase]]
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[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Batt, S M.]]
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[[Category: Besra, G S.]]
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[[Category: Futterer, K.]]
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[[Category: Alpha/beta fold]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 15:39, 10 July 2013

Template:STRUCTURE 4kw5

M. tuberculosis DprE1 in complex with inhibitor TCA1

Template:ABSTRACT PUBMED 23776209

About this Structure

4kw5 is a 2 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

Reference

  • Wang F, Sambandan D, Halder R, Wang J, Batt SM, Weinrick B, Ahmad I, Yang P, Zhang Y, Kim J, Hassani M, Huszar S, Trefzer C, Ma Z, Kaneko T, Mdluli KE, Franzblau S, Chatterjee AK, Johnson K, Mikusova K, Besra GS, Futterer K, Jacobs WR Jr, Schultz PG. Identification of a small molecule with activity against drug-resistant and persistent tuberculosis. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2510-7. doi:, 10.1073/pnas.1309171110. Epub 2013 Jun 17. PMID:23776209 doi:10.1073/pnas.1309171110

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OCA

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