4key
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4key| PDB=4key | SCENE= }} | |
+ | ===Structure of P450 BM3 A82F F87V in complex with omeprazole=== | ||
- | The | + | ==Function== |
+ | [[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450. | ||
- | + | ==About this Structure== | |
- | + | [[4key]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEY OCA]. | |
- | + | [[Category: Bacillus megaterium]] | |
+ | [[Category: Leys, D.]] | ||
+ | [[Category: Monooxygenase]] | ||
+ | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
+ | [[Category: P450 heme domain]] |
Revision as of 15:54, 10 July 2013
Structure of P450 BM3 A82F F87V in complex with omeprazole
Function
[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.
About this Structure
4key is a 2 chain structure with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.