4iru
From Proteopedia
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{{STRUCTURE_4iru| PDB=4iru | SCENE= }} | {{STRUCTURE_4iru| PDB=4iru | SCENE= }} | ||
===Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3=== | ===Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3=== | ||
| + | {{ABSTRACT_PUBMED_23821544}} | ||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4iru]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRU OCA]. | [[4iru]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IRU OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023821544</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]] | [[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]] | ||
Revision as of 04:31, 18 July 2013
Contents |
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Template:ABSTRACT PUBMED 23821544
Function
[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
About this Structure
4iru is a 6 chain structure with sequence from Homo sapiens and Legionella pneumophila subsp. pneumophila str. philadelphia 1. Full crystallographic information is available from OCA.
Reference
- Mishra AK, Del Campo CM, Collins RE, Roy CR, Lambright DG. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-Canonical Hydrolytic Mechanism. J Biol Chem. 2013 Jul 2. PMID:23821544 doi:10.1074/jbc.M113.470625
Categories: Homo sapiens | Legionella pneumophila subsp. pneumophila str. philadelphia 1 | Small monomeric GTPase | Collins, R E. | Delcampo, C M. | Lambright, D G. | Mishra, A K. | Roy, C R. | Arginine finger | Glutamate finger | Gtp hydrolysis | Gtp hydrolysis activator | Hydrolase-hydrolase complex | Intrinsic gtpase activity | Nucleotide binding | P-loop motif | Protein transport
