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4i4b

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'''Unreleased structure'''
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{{STRUCTURE_4i4b| PDB=4i4b | SCENE= }}
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===HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA===
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{{ABSTRACT_PUBMED_23802607}}
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The entry 4i4b is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/MVAA_PSEMV MVAA_PSEMV]] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
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Authors: Stauffacher, C.V., Steussy, C.N., Critchelow, C.J., Schmidt, T., Min, J., Wrensford, L.V., Burgner, J.W., Rodwell, V.W.
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==About this Structure==
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[[4i4b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_mevalonii Pseudomonas mevalonii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I4B OCA].
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Description: HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA
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==Reference==
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<ref group="xtra">PMID:023802607</ref><references group="xtra"/><references/>
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[[Category: Hydroxymethylglutaryl-CoA reductase]]
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[[Category: Pseudomonas mevalonii]]
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[[Category: Burgner, J W.]]
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[[Category: Critchelow, C J.]]
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[[Category: Min, J.]]
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[[Category: Rodwell, V W.]]
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[[Category: Schmidt, T.]]
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[[Category: Stauffacher, C V.]]
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[[Category: Steussy, C N.]]
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[[Category: Wrensford, L V.]]
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[[Category: Oxidoreductase]]

Revision as of 04:56, 18 July 2013

Template:STRUCTURE 4i4b

Contents

HMG-CoA Reductase from Pseudomonas mevalonii complexed with NAD and intermediate hemiacetal form of HMG-CoA

Template:ABSTRACT PUBMED 23802607

Function

[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.

About this Structure

4i4b is a 2 chain structure with sequence from Pseudomonas mevalonii. Full crystallographic information is available from OCA.

Reference

  • Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g

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OCA

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