4jeh
From Proteopedia
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| - | + | {{STRUCTURE_4jeh| PDB=4jeh | SCENE= }} | |
| + | ===Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/STXB1_RAT STXB1_RAT]] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. [[http://www.uniprot.org/uniprot/STX1A_RAT STX1A_RAT]] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. | ||
| - | + | ==About this Structure== | |
| - | + | [[4jeh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JEH OCA]. | |
| - | + | [[Category: Rattus norvegicus]] | |
| + | [[Category: Burkhardt, P.]] | ||
| + | [[Category: Colbert, K N.]] | ||
| + | [[Category: Fasshauer, D.]] | ||
| + | [[Category: Hattendorf, D A.]] | ||
| + | [[Category: Weis, W I.]] | ||
| + | [[Category: Weiss, T M.]] | ||
| + | [[Category: Endocytosis-exocytosis complex]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Neurotransmitter transport]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Transmembrane]] | ||
| + | [[Category: Transport]] | ||
Revision as of 05:03, 18 July 2013
Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex
Function
[STXB1_RAT] May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions. [STX1A_RAT] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
About this Structure
4jeh is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
