This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4keo

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{STRUCTURE_4keo| PDB=4keo | SCENE= }}
 +
===Structure of human folate receptor alpha in complex with folic acid===
-
The entry 4keo is ON HOLD until Paper Publication
+
==Disease==
 +
[[http://www.uniprot.org/uniprot/FOLR1_HUMAN FOLR1_HUMAN]] Neurodegenerative syndrome due to cerebral folate transport deficiency. Neurodegeneration due to cerebral folate transport deficiency (NCFTD) [MIM:[http://omim.org/entry/613068 613068]]: A neurodegenerative disorder resulting from brain-specific folate deficiency early in life. Onset is apparent in late infancy with severe developmental regression, movement disturbances, epilepsy and leukodystrophy. Note=The disease is caused by mutations affecting the gene represented in this entry.
-
Authors: Ke, J., Chen, C., Zhou, X.E., Brunzelle, J.S., Yi, W., Li, J., Young, E.-L., Xu, H.E., Melcher, K.
+
==Function==
 +
[[http://www.uniprot.org/uniprot/FOLR1_HUMAN FOLR1_HUMAN]] Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
-
Description: Structure of human folate receptor alpha in complex with folic acid
+
==About this Structure==
 +
[[4keo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEO OCA].
 +
[[Category: Homo sapiens]]
 +
[[Category: Brunzelle, J S.]]
 +
[[Category: Chen, C.]]
 +
[[Category: Ke, J.]]
 +
[[Category: Li, J.]]
 +
[[Category: Melcher, K.]]
 +
[[Category: Xu, H E.]]
 +
[[Category: Yi, W.]]
 +
[[Category: Young, E L.]]
 +
[[Category: Zhou, X E.]]
 +
[[Category: Cysteine-rich glycoprotein]]
 +
[[Category: Folate binding protein]]
 +
[[Category: Folate receptor]]
 +
[[Category: Folic acid binding]]
 +
[[Category: Frizzled-like fold]]
 +
[[Category: Frizzled-like structure]]
 +
[[Category: Membrane]]
 +
[[Category: Receptor-ligand complex]]

Revision as of 05:11, 18 July 2013

Template:STRUCTURE 4keo

Contents

Structure of human folate receptor alpha in complex with folic acid

Disease

[FOLR1_HUMAN] Neurodegenerative syndrome due to cerebral folate transport deficiency. Neurodegeneration due to cerebral folate transport deficiency (NCFTD) [MIM:613068]: A neurodegenerative disorder resulting from brain-specific folate deficiency early in life. Onset is apparent in late infancy with severe developmental regression, movement disturbances, epilepsy and leukodystrophy. Note=The disease is caused by mutations affecting the gene represented in this entry.

Function

[FOLR1_HUMAN] Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.

About this Structure

4keo is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4keo"
Personal tools