1hjf
From Proteopedia
(Difference between revisions)
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| - | [[Image:1hjf.png|left|200px]] | ||
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{{STRUCTURE_1hjf| PDB=1hjf | SCENE= }} | {{STRUCTURE_1hjf| PDB=1hjf | SCENE= }} | ||
| + | ===Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258=== | ||
| + | {{ABSTRACT_PUBMED_11279000}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/CEFE_STRC2 CEFE_STRC2]] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011279000</ref>< | + | <ref group="xtra">PMID:011279000</ref><references group="xtra"/><references/> |
[[Category: Streptomyces clavuligerus]] | [[Category: Streptomyces clavuligerus]] | ||
[[Category: Baldwin, J E.]] | [[Category: Baldwin, J E.]] | ||
Revision as of 11:06, 24 July 2013
Contents |
Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase: The role of arginine-258
Template:ABSTRACT PUBMED 11279000
Function
[CEFE_STRC2] Catalyzes the step from penicillin N to deacetoxy-cephalosporin C.
About this Structure
1hjf is a 1 chain structure with sequence from Streptomyces clavuligerus. Full crystallographic information is available from OCA.
Reference
- Lee HJ, Lloyd MD, Clifton IJ, Harlos K, Dubus A, Baldwin JE, Frere JM, Schofield CJ. Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. J Biol Chem. 2001 May 25;276(21):18290-5. Epub 2001 Feb 21. PMID:11279000 doi:http://dx.doi.org/10.1074/jbc.M100085200
Categories: Streptomyces clavuligerus | Baldwin, J E. | Clifton, I J. | Dubus, A. | Frere, J M. | Harlos, K. | Lee, H J. | Lloyd, M D. | Schofield, C J. | 2- oxoglutarate-dependent oxygenase | Alternative 2-oxoacid | Cephem antibiotic biosynthesis | Chemical cosubstrate rescue | Co-substrate selectivity | Oxidoreductase
