3n5g
From Proteopedia
(Difference between revisions)
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| - | [[Image:3n5g.png|left|200px]] | ||
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{{STRUCTURE_3n5g| PDB=3n5g | SCENE= }} | {{STRUCTURE_3n5g| PDB=3n5g | SCENE= }} | ||
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===Crystal Structure of histidine-tagged human thymidylate synthase=== | ===Crystal Structure of histidine-tagged human thymidylate synthase=== | ||
| + | {{ABSTRACT_PUBMED_21795601}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Thymidylate synthase|Thymidylate synthase]] | *[[Thymidylate synthase|Thymidylate synthase]] | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021795601</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
Revision as of 11:43, 24 July 2013
Contents |
Crystal Structure of histidine-tagged human thymidylate synthase
Template:ABSTRACT PUBMED 21795601
Function
[TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.[1]
About this Structure
3n5g is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cardinale D, Guaitoli G, Tondi D, Luciani R, Henrich S, Salo-Ahen OM, Ferrari S, Marverti G, Guerrieri D, Ligabue A, Frassineti C, Pozzi C, Mangani S, Fessas D, Guerrini R, Ponterini G, Wade RC, Costi MP. Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):E542-9. doi:, 10.1073/pnas.1104829108. Epub 2011 Jul 27. PMID:21795601 doi:10.1073/pnas.1104829108
- ↑ Anderson DD, Quintero CM, Stover PJ. Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15163-8. doi:, 10.1073/pnas.1103623108. Epub 2011 Aug 26. PMID:21876188 doi:10.1073/pnas.1103623108
