4fps

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m (Protected "4fps" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4fps| PDB=4fps | SCENE= }}
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===tRNA-Guanine Transglycosylase in complex with adamantyl-substituted lin-benzoguanine ligand===
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The entry 4fps is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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Authors: Immekus, F., Klebe, G.
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==About this Structure==
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[[4fps]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_zm4_=_atcc_31821 Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FPS OCA].
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Description: tRNA-Guanine Transglycosylase in complex with adamantyl-substituted lin-benzoguanine ligand
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[[Category: Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]]
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[[Category: Immekus, F.]]
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[[Category: Klebe, G.]]
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[[Category: Biosynthesis]]
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[[Category: Glycosyltransferase]]
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[[Category: Queuosine]]
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[[Category: Tim barrel]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Trna]]
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[[Category: Trna processing]]

Revision as of 13:02, 24 July 2013

Template:STRUCTURE 4fps

tRNA-Guanine Transglycosylase in complex with adamantyl-substituted lin-benzoguanine ligand

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4fps is a 1 chain structure with sequence from Zymomonas mobilis subsp. mobilis zm4 = atcc 31821. Full crystallographic information is available from OCA.

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OCA

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