4i2f
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4i2f| PDB=4i2f | SCENE= }} | |
+ | ===Binary complex of mouse TdT with ssDNA=== | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | ||
- | + | ==About this Structure== | |
- | + | [[4i2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I2F OCA]. | |
- | + | [[Category: DNA nucleotidylexotransferase]] | |
+ | [[Category: Mus musculus]] | ||
+ | [[Category: Delarue, M.]] | ||
+ | [[Category: Gouge, J.]] | ||
+ | [[Category: Terminal transferase]] | ||
+ | [[Category: Transferase-dna complex]] |
Revision as of 13:11, 24 July 2013
Binary complex of mouse TdT with ssDNA
Function
[TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
About this Structure
4i2f is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.