4i2g

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'''Unreleased structure'''
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{{STRUCTURE_4i2g| PDB=4i2g | SCENE= }}
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===Binary complex of mouse TdT with ssDNA===
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The entry 4i2g is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
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Authors: Gouge, J., Delarue, M.
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==About this Structure==
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[[4i2g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I2G OCA].
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Description: Binary complex of mouse TdT with ssDNA
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[[Category: DNA nucleotidylexotransferase]]
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[[Category: Mus musculus]]
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[[Category: Delarue, M.]]
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[[Category: Gouge, J.]]
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[[Category: Terminal transferase]]
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[[Category: Transferase-dna complex]]

Revision as of 13:11, 24 July 2013

Template:STRUCTURE 4i2g

Binary complex of mouse TdT with ssDNA

Function

[TDT_MOUSE] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

About this Structure

4i2g is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

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OCA

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