4jph

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'''Unreleased structure'''
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{{STRUCTURE_4jph| PDB=4jph | SCENE= }}
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===Crystal structure of Protein Related to DAN and Cerberus (PRDC)===
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The entry 4jph is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/GREM2_MOUSE GREM2_MOUSE]] Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.<ref>PMID:15039429</ref>
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Authors: Deng, X., Nolan, K.T., Kattamuri, C., Thompson, T.B.
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==About this Structure==
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[[4jph]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JPH OCA].
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Description: Crystal structure of Protein Related to DAN and Cerberus (PRDC)
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Deng, X.]]
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[[Category: Kattamuri, C.]]
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[[Category: Nolan, K T.]]
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[[Category: Thompson, T B.]]
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[[Category: Bmp antagonist]]
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[[Category: Bmp-2]]
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[[Category: Bmp-4]]
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[[Category: Bmp-7]]
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[[Category: Can domain]]
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[[Category: Cystine knot]]
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[[Category: Cytokine]]
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[[Category: Dan domain]]
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[[Category: Extracellular]]
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[[Category: Gdf-5]]
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[[Category: Gsh]]

Revision as of 13:12, 24 July 2013

Template:STRUCTURE 4jph

Contents

Crystal structure of Protein Related to DAN and Cerberus (PRDC)

Function

[GREM2_MOUSE] Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner. Antagonized BMP4-induced suppression of progesterone production in granulosa cells.[1]

About this Structure

4jph is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Sudo S, Avsian-Kretchmer O, Wang LS, Hsueh AJ. Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation. J Biol Chem. 2004 May 28;279(22):23134-41. Epub 2004 Mar 23. PMID:15039429 doi:10.1074/jbc.M402376200

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OCA

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