Sandbox 126
From Proteopedia
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<scene name='37/372726/Pbp2a/1'>PBP2a resticted *b</scene> | <scene name='37/372726/Pbp2a/1'>PBP2a resticted *b</scene> | ||
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Revision as of 17:26, 24 July 2013
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Background
PBP2a is composed of two domains: a non-penicillin binding (NPB) domain and a TP domain. The NBP domain of PBP2a is anchored in the cell membrane, while the TP domain “sits” in the periplasm with its active site facing the inner surface of the cell wall. The active site contains a serine residue at position 403 (Ser403) which catalyzes the cross-linking of the peptidoglycan rows with pentaglycine cross-links.
