4bxs

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'''Unreleased structure'''
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{{STRUCTURE_4bxs| PDB=4bxs | SCENE= }}
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===Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis===
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{{ABSTRACT_PUBMED_23869089}}
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The entry 4bxs is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/FA5V_PSETE FA5V_PSETE]] Snake prothrombin activator that attacks the hemostatic system of prey. This non-catalytic subunit is functionally similar to blood coagulation factor V. It serves as a critical cofactor for the prothrombinase activity of the catalytic subunit, which is similar to the blood coagulation factor X.<ref>PMID:12362232</ref>
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Authors: Lechtenberg, B.C., Murray-Rust, T.A., Johnson, D.J.D., Adams, T.E., Krishnaswamy, S., Camire, R.M., Huntington, J.A.
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==About this Structure==
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[[4bxs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudonaja_textilis Pseudonaja textilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BXS OCA].
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Description: Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis
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==Reference==
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<ref group="xtra">PMID:023869089</ref><references group="xtra"/><references/>
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[[Category: Pseudonaja textilis]]
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[[Category: Adams, T E.]]
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[[Category: Camire, R M.]]
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[[Category: Huntington, J A.]]
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[[Category: Johnson, D J.D.]]
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[[Category: Krishnaswamy, S.]]
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[[Category: Lechtenberg, B C.]]
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[[Category: Murray-Rust, T A.]]
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[[Category: Blood clotting]]
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[[Category: Blood coagulation]]
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[[Category: Hydrolase]]
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[[Category: Prothrombinase]]

Revision as of 05:14, 1 August 2013

Template:STRUCTURE 4bxs

Contents

Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis

Template:ABSTRACT PUBMED 23869089

Function

[FA5V_PSETE] Snake prothrombin activator that attacks the hemostatic system of prey. This non-catalytic subunit is functionally similar to blood coagulation factor V. It serves as a critical cofactor for the prothrombinase activity of the catalytic subunit, which is similar to the blood coagulation factor X.[1]

About this Structure

4bxs is a 2 chain structure with sequence from Pseudonaja textilis. Full crystallographic information is available from OCA.

Reference

  • Lechtenberg BC, Murray-Rust TA, Johnson DJ, Adams TE, Krishnaswamy S, Camire RM, Huntington JA. Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis. Blood. 2013 Jul 18. PMID:23869089 doi:10.1182/blood-2013-06-511733
  1. ↑ Rao VS, Kini RM. Pseutarin C, a prothrombin activator from Pseudonaja textilis venom: its structural and functional similarity to mammalian coagulation factor Xa-Va complex. Thromb Haemost. 2002 Oct;88(4):611-9. PMID:12362232 doi:10.1267/th02100611

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