4hm9

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'''Unreleased structure'''
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{{STRUCTURE_4hm9| PDB=4hm9 | SCENE= }}
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===Crystal structure of full-length human catenin-beta-like 1===
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The entry 4hm9 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/CTBL1_HUMAN CTBL1_HUMAN]] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.<ref>PMID:12659813</ref> <ref>PMID:18722174</ref>
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Authors: Du, Z., Huang, X., Wang, G., Wu, Y.
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==About this Structure==
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[[4hm9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM9 OCA].
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Description: Crystal structure of full-length human catenin-beta-like 1
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Du, Z.]]
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[[Category: Huang, X.]]
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[[Category: Wang, G.]]
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[[Category: Wu, Y.]]
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[[Category: All alpha-helical]]
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[[Category: Armadillo repeat]]
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[[Category: Protein transport]]

Revision as of 05:18, 1 August 2013

Template:STRUCTURE 4hm9

Contents

Crystal structure of full-length human catenin-beta-like 1

Function

[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]

About this Structure

4hm9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
  2. ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009

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OCA

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