4e8b

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[[Image:4e8b.jpg|left|200px]]
 
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{{STRUCTURE_4e8b| PDB=4e8b | SCENE= }}
{{STRUCTURE_4e8b| PDB=4e8b | SCENE= }}
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===Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli===
===Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli===
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{{ABSTRACT_PUBMED_22925577}}
{{ABSTRACT_PUBMED_22925577}}
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==Function==
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[[http://www.uniprot.org/uniprot/RSME_ECOLI RSME_ECOLI]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.<ref>PMID:16431987</ref> <ref>PMID:17872509</ref>
==About this Structure==
==About this Structure==
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[[4e8b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E8B OCA].
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[[4e8b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E8B OCA].
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[[Category: Escherichia coli]]
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==Reference==
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<ref group="xtra">PMID:022925577</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli k-12]]
[[Category: Dong, Y H.]]
[[Category: Dong, Y H.]]
[[Category: Gao, Z Q.]]
[[Category: Gao, Z Q.]]

Revision as of 19:05, 7 August 2013

Template:STRUCTURE 4e8b

Contents

Crystal structure of 16S rRNA Methyltransferase RsmE from E.coli

Template:ABSTRACT PUBMED 22925577

Function

[RSME_ECOLI] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.[1] [2]

About this Structure

4e8b is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Zhang H, Wan H, Gao ZQ, Wei Y, Wang WJ, Liu GF, Shtykova EV, Xu JH, Dong YH. Insights into the Catalytic Mechanism of 16S rRNA Methyltransferase RsmE (m(3)U1498) from Crystal and Solution Structures. J Mol Biol. 2012 Aug 25. PMID:22925577 doi:10.1016/j.jmb.2012.08.016
  1. ↑ Basturea GN, Rudd KE, Deutscher MP. Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family. RNA. 2006 Mar;12(3):426-34. Epub 2006 Jan 23. PMID:16431987 doi:10.1261/rna.2283106
  2. ↑ Basturea GN, Deutscher MP. Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA. 2007 Nov;13(11):1969-76. Epub 2007 Sep 13. PMID:17872509 doi:rna.700507

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