4imi

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'''Unreleased structure'''
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{{STRUCTURE_4imi| PDB=4imi | SCENE= }}
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===Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72.===
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{{ABSTRACT_PUBMED_23844594}}
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The entry 4imi is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SYMPK_DROME SYMPK_DROME]] Component of a protein complex required for cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.<ref>PMID:18042462</ref> <ref>PMID:19450530</ref>
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Authors: Luo, Y., Yogesha, S.D., Zhang, Y.
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==About this Structure==
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[[4imi]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IMI OCA].
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Description: Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72.
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==Reference==
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<ref group="xtra">PMID:023844594</ref><references group="xtra"/><references/>
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[[Category: Drosophila melanogaster]]
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[[Category: Phosphoprotein phosphatase]]
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[[Category: Luo, Y.]]
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[[Category: Yogesha, S D.]]
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[[Category: Zhang, Y.]]
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[[Category: Ctd]]
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[[Category: Ctd phosphatase]]
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[[Category: Hydrolase]]
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[[Category: Phosphorylated thr4]]
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[[Category: Ssu72]]
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[[Category: Symplekin]]

Revision as of 20:49, 7 August 2013

Template:STRUCTURE 4imi

Contents

Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72.

Template:ABSTRACT PUBMED 23844594

Function

[SYMPK_DROME] Component of a protein complex required for cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA.[1] [2]

About this Structure

4imi is a 5 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Luo Y, Yogesha SD, Cannon JR, Yan W, Ellington AD, Brodbelt JS, Zhang Y. Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72. ACS Chem Biol. 2013 Jul 23. PMID:23844594 doi:10.1021/cb400229c
  1. Wagner EJ, Burch BD, Godfrey AC, Salzler HR, Duronio RJ, Marzluff WF. A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing. Mol Cell. 2007 Nov 30;28(4):692-9. PMID:18042462 doi:10.1016/j.molcel.2007.10.009
  2. Sullivan KD, Steiniger M, Marzluff WF. A core complex of CPSF73, CPSF100, and Symplekin may form two different cleavage factors for processing of poly(A) and histone mRNAs. Mol Cell. 2009 May 15;34(3):322-32. doi: 10.1016/j.molcel.2009.04.024. PMID:19450530 doi:10.1016/j.molcel.2009.04.024

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