3zei

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-	'''Unreleased structure'''	+	{{STRUCTURE_3zei| PDB=3zei | SCENE= }}
		+	===Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor===
		+	{{ABSTRACT_PUBMED_23879381}}
-	The entry 3zei is ON HOLD until Paper Publication	+	==Function==
		+	[[http://www.uniprot.org/uniprot/CYSK_MYCTU CYSK_MYCTU]] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.
-	Authors: Poyraz, O., Schnell, R., Schneider, G.	+	==About this Structure==
		+	[[3zei]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZEI OCA].
-	Description: Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor	+	==Reference==
		+	<ref group="xtra">PMID:023879381</ref><references group="xtra"/><references/>
		+	[[Category: Cysteine synthase]]
		+	[[Category: Mycobacterium tuberculosis]]
		+	[[Category: Poyraz, O.]]
		+	[[Category: Schneider, G.]]
		+	[[Category: Schnell, R.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]

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Revision as of 20:50, 7 August 2013

Template:STRUCTURE 3zei

Contents 1 Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor 2 Function 3 About this Structure 4 Reference

Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor

Template:ABSTRACT PUBMED 23879381

Function

[CYSK_MYCTU] Catalyzes the conversion of O-acetylserine (OAS) to cysteine through the elimination of acetate and addition of hydrogen sulfide.

About this Structure

3zei is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

• Poyraz O, Jeankumar VU, Saxena S, Schnell R, Haraldsson M, Yogeeswari P, Sriram D, Schneider G. Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis. J Med Chem. 2013 Jul 23. PMID:23879381 doi:10.1021/jm400710k