4b3z

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'''Unreleased structure'''
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{{STRUCTURE_4b3z| PDB=4b3z | SCENE= }}
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===Structure of the human collapsin response mediator protein-1, a lung cancer suppressor===
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The entry 4b3z is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DPYL1_HUMAN DPYL1_HUMAN]] Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.<ref>PMID:11562390</ref>
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Authors: Liu, S.H., Lin, Y.H., Huang, S.F., Niou, Y.K., Huang, L.L., Chen, Y.J.
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==About this Structure==
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[[4b3z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B3Z OCA].
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Description: Structure of the human collapsin response mediator protein-1, a lung cancer suppressor
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Chen, Y J.]]
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[[Category: Huang, L L.]]
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[[Category: Huang, S F.]]
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[[Category: Lin, Y H.]]
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[[Category: Liu, S H.]]
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[[Category: Niou, Y K.]]
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[[Category: Hydrolase]]
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[[Category: Lung cancer suppressor]]
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[[Category: Non-small-cell lung cancer]]
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[[Category: Semaphorin 3a]]
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[[Category: Tim barrel]]

Revision as of 20:58, 7 August 2013

Template:STRUCTURE 4b3z

Contents

Structure of the human collapsin response mediator protein-1, a lung cancer suppressor

Function

[DPYL1_HUMAN] Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.[1]

About this Structure

4b3z is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Shih JY, Yang SC, Hong TM, Yuan A, Chen JJ, Yu CJ, Chang YL, Lee YC, Peck K, Wu CW, Yang PC. Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. J Natl Cancer Inst. 2001 Sep 19;93(18):1392-400. PMID:11562390

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