Signal recognition particle receptor

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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase.
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'''Signal recognition particle receptor''' (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the [[Signal recognition particle protein|signal recognition particle (SRP)]]. SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.
==3D structures of SRPR==
==3D structures of SRPR==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
[[1nrj]] – ySRPR α+β subunits + GTP – yeast<br />
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[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
[[2go5]] - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM<br />
[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
[[3dm9]], [[3dmd]], [[3e70 ]]– SRPR + GDP – ''Pyrococcus furiosus''
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'''SRPR FtsY'''
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[[1zu5]], [[1zu4]] – SRPR FtsY NG domain – ''Mycoplasma mycoides''<br />
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[[1vma]] – SRPR FtsY – ''Thermotoga maritima''<br />
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[[2yhs]], [[2qy9]], [[1fts]] – EcSRPR FtsY NG domain – ''Escherichia coli''<br />
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[[2q9a]] – EcSRPR FtsY <br />
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[[2q9c]], [[2q9b]] – EcSRPR FtsY NG domain + GMPPNP<br />
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[[2iyl]] – EcSRPR FtsY residues 20-303 + GDP<br />
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[[3zn8]], [[2xxa]] – EcSRPR FtsY + signal recognition particle protein + RNA<br />
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[[2j7p]], [[1rj9]], [[1okk]] – TaSRPR FtsY NG domain + signal recognition particle protein – ''Thermus aquaticus''<br />
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[[2cnw]] – TaSRPR FtsY NG domain + signal recognition particle protein + GDP<br />
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:34, 13 August 2013

Human SRPR α (grey) and β subunit (green) complex with GTP and Mg+2 (green) ion 2fh5

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Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase. The bacterial SRPR is called FtsY.

3D structures of SRPR

Updated on 13-August-2013

1nrj – ySRPR α+β subunits + GTP – yeast
2fh5 - hSRPR α+β subunits + GTP – human
2ged - ySRPR β subunit (mutant)
2go5 - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM
3dm9, 3dmd, 3e70 – SRPR + GDP – Pyrococcus furiosus

SRPR FtsY

1zu5, 1zu4 – SRPR FtsY NG domain – Mycoplasma mycoides
1vma – SRPR FtsY – Thermotoga maritima
2yhs, 2qy9, 1fts – EcSRPR FtsY NG domain – Escherichia coli
2q9a – EcSRPR FtsY
2q9c, 2q9b – EcSRPR FtsY NG domain + GMPPNP
2iyl – EcSRPR FtsY residues 20-303 + GDP
3zn8, 2xxa – EcSRPR FtsY + signal recognition particle protein + RNA
2j7p, 1rj9, 1okk – TaSRPR FtsY NG domain + signal recognition particle protein – Thermus aquaticus
2cnw – TaSRPR FtsY NG domain + signal recognition particle protein + GDP

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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