3ulc
From Proteopedia
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{{STRUCTURE_3ulc| PDB=3ulc | SCENE= }} | {{STRUCTURE_3ulc| PDB=3ulc | SCENE= }} | ||
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===Crystal structure of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1, a TORC2 subunit, in the P3121 crystal form=== | ===Crystal structure of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1, a TORC2 subunit, in the P3121 crystal form=== | ||
| + | {{ABSTRACT_PUBMED_22505404}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/AVO1_YEAST AVO1_YEAST]] Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3ulc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3ulc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ULC OCA]. |
| - | [[Category: Saccharomyces cerevisiae]] | + | |
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022505404</ref><references group="xtra"/><references/> | ||
| + | [[Category: Saccharomyces cerevisiae s288c]] | ||
[[Category: Matsuura, Y.]] | [[Category: Matsuura, Y.]] | ||
[[Category: Pan, D.]] | [[Category: Pan, D.]] | ||
Revision as of 06:20, 14 August 2013
Contents |
Crystal structure of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1, a TORC2 subunit, in the P3121 crystal form
Template:ABSTRACT PUBMED 22505404
Function
[AVO1_YEAST] Component of TORC2, which regulates cell cycle-dependent polarization of the actin-cytoskeleton and cell wall integrity. TORC2 controls polarity of the actin cytoskeleton, which is required for orienting the secretory pathway toward discrete growth sites, via the RHO1/PKC1/MAPK cell integrity pathway.
About this Structure
3ulc is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
Reference
- Pan D, Matsuura Y. Structures of the pleckstrin homology domain of Saccharomyces cerevisiae Avo1 and its human orthologue Sin1, an essential subunit of TOR complex 2. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):386-92., Epub 2012 Mar 27. PMID:22505404 doi:10.1107/S1744309112007178
