Luciferase
From Proteopedia
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| + | <StructureSection load='3iep' size='450' side='right' scene='Luciferase/Cv/1' caption=''> | ||
[[Image:3iep.png|left|200px|thumb|Crystal Structure of Luciferase [[3iep]]]] | [[Image:3iep.png|left|200px|thumb|Crystal Structure of Luciferase [[3iep]]]] | ||
| - | {{STRUCTURE_3iep| PDB=3iep | SIZE=400| SCENE=Luciferase/Cv/1 |right|CAPTION=Luciferase [[3iep]] }} | ||
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==Additional information== | ==Additional information== | ||
[[Image:2d1s jena3dviewer image.jpg|left|220px]] | [[Image:2d1s jena3dviewer image.jpg|left|220px]] | ||
| - | < | + | <scene name='Luciferase/2d1s/1'>Luciferase</scene> ([[Luciola cruciata luciferase|2d1s]]) {{Link Toggle FancyCartoonHighQualityView}} |
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Several organisms are bioluminescent, meaning that they produce light. Luciferase is one of the enzymes that catalyzes light emitting reactions in organisms. | Several organisms are bioluminescent, meaning that they produce light. Luciferase is one of the enzymes that catalyzes light emitting reactions in organisms. | ||
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*[[Green Fluorescent Protein]] | *[[Green Fluorescent Protein]] | ||
* For additional information, see: [[Colored & Bioluminescent Proteins]] | * For additional information, see: [[Colored & Bioluminescent Proteins]] | ||
| - | + | </StructureSection> | |
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
Revision as of 06:57, 20 August 2013
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References
- ↑ Auld DS, Lovell S, Thorne N, Lea WA, Maloney DJ, Shen M, Rai G, Battaile KP, Thomas CJ, Simeonov A, Hanzlik RP, Inglese J. Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4878-83. Epub 2010 Mar 1. PMID:20194791
- ↑ Campbell ZT, Weichsel A, Montfort WR, Baldwin TO. Crystal Structure of the Bacterial Luciferase:Flavin Complex Provides Insight into the Function of the subunit. Biochemistry. 2009 May 12. PMID:19435287 doi:http://dx.doi.org/10.1021/bi900003t
Additional Literature
- Marques SM, Esteves da Silva JC. Firefly bioluminescence: a mechanistic approach of luciferase catalyzed reactions. IUBMB Life. 2009 Jan;61(1):6-17. PMID:18949818 doi:10.1002/iub.134
- Inouye S. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Cell Mol Life Sci. 2010 Feb;67(3):387-404. Epub 2009 Oct 27. PMID:19859663 doi:10.1007/s00018-009-0170-8
External Resources
- Yahoo news coverage of luciferase studies funded research for military applications
- Luciferase at Wikipedia
- Luciferase: June 2006 Molecule of the Month as part of the series of tutorials that are at the RCSB Protein Data Bank and written by David S. Goodsell
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Wayne Decatur, Alexander Berchansky, Loïc Gazquez, Charlene Planchenault, David Canner
