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4kjk

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'''Unreleased structure'''
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{{STRUCTURE_4kjk| PDB=4kjk | SCENE= }}
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===Room Temperature WT DHFR===
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{{ABSTRACT_PUBMED_23913260}}
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The entry 4kjk is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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Authors: van den Bedem, H., Bhabha, G., Yang, K., Wright, P.E., Fraser, J.S.
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==About this Structure==
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[[4kjk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KJK OCA].
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Description: Room Temperature WT DHFR
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==Reference==
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<ref group="xtra">PMID:023913260</ref><references group="xtra"/><references/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Escherichia coli k-12]]
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[[Category: Bedem, H van den.]]
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[[Category: Bhabha, G.]]
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[[Category: Fraser, J S.]]
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[[Category: Wright, P E.]]
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[[Category: Yang, K.]]
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[[Category: Oxidoreductase]]
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[[Category: Rossman fold]]

Revision as of 08:22, 21 August 2013

Template:STRUCTURE 4kjk

Contents

Room Temperature WT DHFR

Template:ABSTRACT PUBMED 23913260

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4kjk is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS. Automated identification of functional dynamic contact networks from X-ray crystallography. Nat Methods. 2013 Aug 4. doi: 10.1038/nmeth.2592. PMID:23913260 doi:10.1038/nmeth.2592

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OCA

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