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4hm9
From Proteopedia
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{{STRUCTURE_4hm9| PDB=4hm9 | SCENE= }} | {{STRUCTURE_4hm9| PDB=4hm9 | SCENE= }} | ||
===Crystal structure of full-length human catenin-beta-like 1=== | ===Crystal structure of full-length human catenin-beta-like 1=== | ||
| + | {{ABSTRACT_PUBMED_23897482}} | ||
==Function== | ==Function== | ||
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==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023897482</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Du, Z.]] | [[Category: Du, Z.]] | ||
Revision as of 08:24, 21 August 2013
Contents |
Crystal structure of full-length human catenin-beta-like 1
Template:ABSTRACT PUBMED 23897482
Function
[CTBL1_HUMAN] Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.[1] [2]
About this Structure
4hm9 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Huang X, Wang G, Wu Y, Du Z. The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1598-608. doi:, 10.1107/S0907444913011360. Epub 2013 Jul 20. PMID:23897482 doi:10.1107/S0907444913011360
- ↑ Jabbour L, Welter JF, Kollar J, Hering TM. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics. 2003 Mar;81(3):292-303. PMID:12659813
- ↑ Conticello SG, Ganesh K, Xue K, Lu M, Rada C, Neuberger MS. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Mol Cell. 2008 Aug 22;31(4):474-84. doi: 10.1016/j.molcel.2008.07.009. PMID:18722174 doi:10.1016/j.molcel.2008.07.009
