4bhx
From Proteopedia
(Difference between revisions)
m (Protected "4bhx" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
{{STRUCTURE_4bhx| PDB=4bhx | SCENE= }} | {{STRUCTURE_4bhx| PDB=4bhx | SCENE= }} | ||
===Crystal structure of the SCAN domain from human paternally expressed gene 3 protein=== | ===Crystal structure of the SCAN domain from human paternally expressed gene 3 protein=== | ||
| + | {{ABSTRACT_PUBMED_23936039}} | ||
==Function== | ==Function== | ||
| Line 9: | Line 10: | ||
==Reference== | ==Reference== | ||
| - | <references group="xtra"/><references/> | + | <ref group="xtra">PMID:023936039</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Eadsforth, T C.]] | [[Category: Eadsforth, T C.]] | ||
Revision as of 08:26, 21 August 2013
Contents |
Crystal structure of the SCAN domain from human paternally expressed gene 3 protein
Template:ABSTRACT PUBMED 23936039
Function
[PEG3_HUMAN] Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.[1]
About this Structure
4bhx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rimsa V, Eadsforth TC, Hunter WN. Structure of the SCAN Domain of Human Paternally Expressed Gene 3 Protein. PLoS One. 2013 Jul 23;8(7):e69538. doi: 10.1371/journal.pone.0069538. Print 2013. PMID:23936039 doi:10.1371/journal.pone.0069538
