3ps9

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{{STRUCTURE_3ps9| PDB=3ps9 | SCENE= }}
{{STRUCTURE_3ps9| PDB=3ps9 | SCENE= }}
===Crystal structure of MnmC from E. coli===
===Crystal structure of MnmC from E. coli===
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{{ABSTRACT_PUBMED_23617613}}
==Function==
==Function==
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[[http://www.uniprot.org/uniprot/C5W761_ECOBB C5W761_ECOBB]] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).[SAAS:SAAS006076_004_060760][HAMAP-Rule:MF_01102]
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[[http://www.uniprot.org/uniprot/C6ELC9_ECOBD C6ELC9_ECOBD]] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).[SAAS:SAAS006076_004_060760][HAMAP-Rule:MF_01102]
==About this Structure==
==About this Structure==
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[[3ps9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS9 OCA].
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[[3ps9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_bl21 Escherichia coli bl21]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS9 OCA].
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[[Category: Escherichia coli]]
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==Reference==
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<ref group="xtra">PMID:023617613</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli bl21]]
[[Category: Almo, S C.]]
[[Category: Almo, S C.]]
[[Category: Kim, J.]]
[[Category: Kim, J.]]

Revision as of 08:27, 21 August 2013

Template:STRUCTURE 3ps9

Contents

Crystal structure of MnmC from E. coli

Template:ABSTRACT PUBMED 23617613

Function

[C6ELC9_ECOBD] Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity).[SAAS:SAAS006076_004_060760][HAMAP-Rule:MF_01102]

About this Structure

3ps9 is a 1 chain structure with sequence from Escherichia coli bl21. Full crystallographic information is available from OCA.

Reference

  • Kim J, Almo SC. Structural basis for hypermodification of the wobble uridine in tRNA by bifunctional enzyme MnmC. BMC Struct Biol. 2013 Apr 24;13:5. doi: 10.1186/1472-6807-13-5. PMID:23617613 doi:10.1186/1472-6807-13-5

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