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4c11
From Proteopedia
OCA (Talk | contribs)
(New page: {{STRUCTURE_4c11| PDB=4c11 | SCENE= }} ===Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region=== ==Function== [[http://www.uniprot.org/uniprot/Q6DLV0_9...)
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Revision as of 08:32, 21 August 2013
Dengue virus RNA dependent RNA polymerase with residues from the NS5 linker region
Function
[Q6DLV0_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4c11 is a 2 chain structure with sequence from Dengue virus and Zasmidium angulare. Full crystallographic information is available from OCA.
