4ffb
From Proteopedia
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| - | [[Image:4ffb.jpg|left|200px]] | ||
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{{STRUCTURE_4ffb| PDB=4ffb | SCENE= }} | {{STRUCTURE_4ffb| PDB=4ffb | SCENE= }} | ||
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===A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase=== | ===A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase=== | ||
| + | {{ABSTRACT_PUBMED_22904013}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/TBA1_YEAST TBA1_YEAST]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/STU2_YEAST STU2_YEAST]] May play a role in the attachment, organization, and/or dynamics of microtubule ends at the spindle pole body. [[http://www.uniprot.org/uniprot/TBB_YEAST TBB_YEAST]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4ffb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4ffb]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFB OCA]. |
| - | [[Category: Saccharomyces cerevisiae]] | + | |
| + | ==See Also== | ||
| + | *[[Tubulin|Tubulin]] | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022904013</ref><references group="xtra"/><references/> | ||
| + | [[Category: Saccharomyces cerevisiae s288c]] | ||
[[Category: Tubulin GTPase]] | [[Category: Tubulin GTPase]] | ||
[[Category: Ayaz, P.]] | [[Category: Ayaz, P.]] | ||
Revision as of 05:16, 28 August 2013
Contents |
A TOG:alpha/beta-tubulin Complex Structure Reveals Conformation-Based Mechanisms For a Microtubule Polymerase
Template:ABSTRACT PUBMED 22904013
Function
[TBA1_YEAST] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [STU2_YEAST] May play a role in the attachment, organization, and/or dynamics of microtubule ends at the spindle pole body. [TBB_YEAST] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
About this Structure
4ffb is a 3 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
See Also
Reference
- Ayaz P, Ye X, Huddleston P, Brautigam CA, Rice LM. A TOG:alphabeta-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase. Science. 2012 Aug 17;337(6096):857-60. PMID:22904013 doi:10.1126/science.1221698
