4kvm
From Proteopedia
| Line 1: | Line 1: | ||
{{STRUCTURE_4kvm| PDB=4kvm | SCENE= }} | {{STRUCTURE_4kvm| PDB=4kvm | SCENE= }} | ||
===The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog=== | ===The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog=== | ||
| + | {{ABSTRACT_PUBMED_23912279}} | ||
==Function== | ==Function== | ||
| Line 7: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4kvm]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVM OCA]. | [[4kvm]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVM OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023912279</ref><references group="xtra"/><references/> | ||
[[Category: Peptide alpha-N-acetyltransferase]] | [[Category: Peptide alpha-N-acetyltransferase]] | ||
[[Category: Schizosaccharomyces pombe 972h-]] | [[Category: Schizosaccharomyces pombe 972h-]] | ||
Revision as of 05:25, 28 August 2013
Contents |
The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog
Template:ABSTRACT PUBMED 23912279
Function
[NAT1_SCHPO] Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. nat1 anchors ard1 and nat5 to the ribosome and may present the N termini of nascent polypeptides for acetylation (By similarity). [ARD1_SCHPO] Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover (By similarity).
About this Structure
4kvm is a 12 chain structure with sequence from Schizosaccharomyces pombe 972h-. Full crystallographic information is available from OCA.
Reference
- Liszczak G, Goldberg JM, Foyn H, Petersson EJ, Arnesen T, Marmorstein R. Molecular basis for N-terminal acetylation by the heterodimeric NatA complex. Nat Struct Mol Biol. 2013 Aug 4. doi: 10.1038/nsmb.2636. PMID:23912279 doi:10.1038/nsmb.2636
