2mpr
From Proteopedia
(New page: 200px<br /><applet load="2mpr" size="450" color="white" frame="true" align="right" spinBox="true" caption="2mpr, resolution 2.4Å" /> '''MALTOPORIN FROM SALMO...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2mpr.jpg|left|200px]]<br /><applet load="2mpr" size=" | + | [[Image:2mpr.jpg|left|200px]]<br /><applet load="2mpr" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2mpr, resolution 2.4Å" /> | caption="2mpr, resolution 2.4Å" /> | ||
'''MALTOPORIN FROM SALMONELLA TYPHIMURIUM'''<br /> | '''MALTOPORIN FROM SALMONELLA TYPHIMURIUM'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The maltodextrin-specific (malto-)porin from Salmonella typhimurium has | + | The maltodextrin-specific (malto-)porin from Salmonella typhimurium has been crystallized. Its three-dimensional structure was determined at 2.4 A resolution (1 A = 0.1 nm). A comparison with the structure of the homologous porin from Escherichia coli as well as with the sequences of other related porins showed that there are regions of appreciable sequence and structure variability, despite close overall similarity. The maltoporin structure was analyzed with a bound nitrophenyl-maltotrioside as well as without ligand. Maltotrioside binding had a negligible effect on the polypeptide structure. It binds at the pore eyelet assuming a conformation close to the natural amylose helix. |
==About this Structure== | ==About this Structure== | ||
| - | 2MPR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with CA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 2MPR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MPR OCA]. |
==Reference== | ==Reference== | ||
| Line 13: | Line 13: | ||
[[Category: Salmonella typhimurium]] | [[Category: Salmonella typhimurium]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Meyer, J | + | [[Category: Meyer, J E.W.]] |
| - | [[Category: Schulz, G | + | [[Category: Schulz, G E.]] |
[[Category: CA]] | [[Category: CA]] | ||
[[Category: oligosaccharide binding]] | [[Category: oligosaccharide binding]] | ||
| Line 21: | Line 21: | ||
[[Category: sugar transport]] | [[Category: sugar transport]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:07:53 2008'' |
Revision as of 16:07, 21 February 2008
|
MALTOPORIN FROM SALMONELLA TYPHIMURIUM
Overview
The maltodextrin-specific (malto-)porin from Salmonella typhimurium has been crystallized. Its three-dimensional structure was determined at 2.4 A resolution (1 A = 0.1 nm). A comparison with the structure of the homologous porin from Escherichia coli as well as with the sequences of other related porins showed that there are regions of appreciable sequence and structure variability, despite close overall similarity. The maltoporin structure was analyzed with a bound nitrophenyl-maltotrioside as well as without ligand. Maltotrioside binding had a negligible effect on the polypeptide structure. It binds at the pore eyelet assuming a conformation close to the natural amylose helix.
About this Structure
2MPR is a Single protein structure of sequence from Salmonella typhimurium with as ligand. Full crystallographic information is available from OCA.
Reference
Structure of maltoporin from Salmonella typhimurium ligated with a nitrophenyl-maltotrioside., Meyer JE, Hofnung M, Schulz GE, J Mol Biol. 1997 Mar 7;266(4):761-75. PMID:9102468
Page seeded by OCA on Thu Feb 21 18:07:53 2008
