4jfl

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'''Unreleased structure'''
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{{STRUCTURE_4jfl| PDB=4jfl | SCENE= }}
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===Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one===
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{{ABSTRACT_PUBMED_23647266}}
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The entry 4jfl is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/FKBP5_HUMAN FKBP5_HUMAN]] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
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Authors: Wang, Y., Kirschner, A., Fabian, A., Gopalakrishnan, R., Kress, C., Hoogeland, B., Koch, U., Kozany, C., Bracher, A., Hausch, F.
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==About this Structure==
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[[4jfl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JFL OCA].
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Description: Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one
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==Reference==
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<ref group="xtra">PMID:023647266</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Bracher, A.]]
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[[Category: Fabian, A.]]
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[[Category: Gopalakrishnan, R.]]
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[[Category: Hausch, F.]]
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[[Category: Hoogeland, B.]]
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[[Category: Kirschner, A.]]
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[[Category: Koch, U.]]
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[[Category: Kozany, C.]]
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[[Category: Kress, C.]]
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[[Category: Wang, Y.]]
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[[Category: Fk-506 binding domain]]
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[[Category: Hsp90 cochaperone]]
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[[Category: Immunophiline]]
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[[Category: Isomerase]]
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[[Category: Peptidyl-prolyl isomerase]]

Revision as of 07:30, 28 August 2013

Template:STRUCTURE 4jfl

Contents

Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one

Template:ABSTRACT PUBMED 23647266

Function

[FKBP5_HUMAN] Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.

About this Structure

4jfl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang Y, Kirschner A, Fabian AK, Gopalakrishnan R, Kress C, Hoogeland B, Koch U, Kozany C, Bracher A, Hausch F. Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J Med Chem. 2013 May 23;56(10):3922-35. doi: 10.1021/jm400087k. Epub 2013 May 6. PMID:23647266 doi:10.1021/jm400087k

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OCA

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