4juo
From Proteopedia
(Difference between revisions)
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- | + | {{STRUCTURE_4juo| PDB=4juo | SCENE= }} | |
+ | ===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32=== | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> | ||
- | + | ==About this Structure== | |
+ | [[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA]. | ||
- | + | ==Reference== | |
+ | <references group="xtra"/><references/> | ||
+ | [[Category: Gekko coi]] | ||
+ | [[Category: Streptococcus pneumoniae tigr4]] | ||
+ | [[Category: Crevel, I.]] | ||
+ | [[Category: Fisher, L M.]] | ||
+ | [[Category: Laponogov, I.]] | ||
+ | [[Category: Pan, X S.]] | ||
+ | [[Category: Sanderson, M R.]] | ||
+ | [[Category: Veselkov, D A.]] | ||
+ | [[Category: Atp binding]] | ||
+ | [[Category: Full-length pare]] | ||
+ | [[Category: Isomerase-dna complex]] | ||
+ | [[Category: Open n-gate]] | ||
+ | [[Category: Parc55]] | ||
+ | [[Category: Topoisomerase iia]] |
Revision as of 07:38, 28 August 2013
Contents |
A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32
Function
[PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[1] [2] [PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[3] [4]
About this Structure
4juo is a 6 chain structure with sequence from Gekko coi and Streptococcus pneumoniae tigr4. Full crystallographic information is available from OCA.
Reference
- ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
- ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338
- ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
- ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338