4juo

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'''Unreleased structure'''
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{{STRUCTURE_4juo| PDB=4juo | SCENE= }}
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===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===
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The entry 4juo is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref> [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>
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Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Crevel, I., Fisher, L.M., Sanderson, M.R.
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==About this Structure==
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[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].
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Description: A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Gekko coi]]
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[[Category: Streptococcus pneumoniae tigr4]]
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[[Category: Crevel, I.]]
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[[Category: Fisher, L M.]]
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[[Category: Laponogov, I.]]
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[[Category: Pan, X S.]]
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[[Category: Sanderson, M R.]]
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[[Category: Veselkov, D A.]]
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[[Category: Atp binding]]
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[[Category: Full-length pare]]
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[[Category: Isomerase-dna complex]]
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[[Category: Open n-gate]]
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[[Category: Parc55]]
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[[Category: Topoisomerase iia]]

Revision as of 07:38, 28 August 2013

Template:STRUCTURE 4juo

Contents

A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32

Function

[PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[1] [2] [PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[3] [4]

About this Structure

4juo is a 6 chain structure with sequence from Gekko coi and Streptococcus pneumoniae tigr4. Full crystallographic information is available from OCA.

Reference

  1. Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
  2. Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338
  3. Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
  4. Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338

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