3ink
From Proteopedia
(Difference between revisions)
| Line 15: | Line 15: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017832837</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brandhuber, B J.]] | [[Category: Brandhuber, B J.]] | ||
[[Category: Mckay, D B.]] | [[Category: Mckay, D B.]] | ||
[[Category: Cytokine]] | [[Category: Cytokine]] | ||
Revision as of 08:52, 4 September 2013
Contents |
UNRAVELING THE STRUCTURE OF INTERLEUKIN-2: REPLY
Disease
[IL2_HUMAN] Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
Function
[IL2_HUMAN] Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
About this Structure
3ink is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- McKay DB. Response. Science. 1992 Jul 17;257(5068):412-3. PMID:17832837 doi:10.1126/science.257.5068.412
