4fuw
From Proteopedia
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{{STRUCTURE_4fuw| PDB=4fuw | SCENE= }} | {{STRUCTURE_4fuw| PDB=4fuw | SCENE= }} | ||
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===Crystal structure of Ego3 mutant=== | ===Crystal structure of Ego3 mutant=== | ||
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{{ABSTRACT_PUBMED_23123112}} | {{ABSTRACT_PUBMED_23123112}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/SLM4_YEAST SLM4_YEAST]] Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy.<ref>PMID:15989961</ref> <ref>PMID:16732272</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[4fuw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUW OCA]. | [[4fuw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FUW OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023123112</ref><references group="xtra"/><references/> | ||
[[Category: Saccharomyces cerevisiae s288c]] | [[Category: Saccharomyces cerevisiae s288c]] | ||
[[Category: Ding, J.]] | [[Category: Ding, J.]] | ||
Revision as of 08:53, 4 September 2013
Contents |
Crystal structure of Ego3 mutant
Template:ABSTRACT PUBMED 23123112
Function
[SLM4_YEAST] Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome. Component of the EGO complex, a complex involved in the regulation of microautophagy.[1] [2]
About this Structure
4fuw is a 2 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
Reference
- Zhang T, Peli-Gulli MP, Yang H, De Virgilio C, Ding J. Ego3 Functions as a Homodimer to Mediate the Interaction between Gtr1-Gtr2 and Ego1 in the EGO Complex to Activate TORC1. Structure. 2012 Oct 30. pii: S0969-2126(12)00372-3. doi:, 10.1016/j.str.2012.09.019. PMID:23123112 doi:10.1016/j.str.2012.09.019
- ↑ Dubouloz F, Deloche O, Wanke V, Cameroni E, De Virgilio C. The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell. 2005 Jul 1;19(1):15-26. PMID:15989961 doi:10.1016/j.molcel.2005.05.020
- ↑ Gao M, Kaiser CA. A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol. 2006 Jul;8(7):657-67. Epub 2006 May 28. PMID:16732272 doi:ncb1419
