This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4gi4
From Proteopedia
| Line 1: | Line 1: | ||
| - | + | {{STRUCTURE_4gi4| PDB=4gi4 | SCENE= }} | |
| + | ===tRNA Guanine Transglycosylase in complex with disubstituted lin-benzoguanine inhibitor=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] | ||
| - | + | ==About this Structure== | |
| - | + | [[4gi4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis_subsp._mobilis_zm4_=_atcc_31821 Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GI4 OCA]. | |
| - | + | [[Category: Zymomonas mobilis subsp. mobilis zm4 = atcc 31821]] | |
| + | [[Category: Immekus, F.]] | ||
| + | [[Category: Klebe, G.]] | ||
| + | [[Category: Biosynthesis]] | ||
| + | [[Category: Queuosine]] | ||
| + | [[Category: Tim barrel glycosyltransferase]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
| + | [[Category: Trna]] | ||
| + | [[Category: Trna processing]] | ||
Revision as of 10:56, 4 September 2013
tRNA Guanine Transglycosylase in complex with disubstituted lin-benzoguanine inhibitor
Function
[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
About this Structure
4gi4 is a 1 chain structure with sequence from Zymomonas mobilis subsp. mobilis zm4 = atcc 31821. Full crystallographic information is available from OCA.
