4ld0
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4ld0| PDB=4ld0 | SCENE= }} | |
| + | ===T. thermophilus RuvC in complex with Holliday junction substrate=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/RUVC_THET8 RUVC_THET8]] Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity). | ||
| - | + | ==About this Structure== | |
| - | + | [[4ld0]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LD0 OCA]. | |
| - | + | [[Category: Crossover junction endodeoxyribonuclease]] | |
| + | [[Category: Thermus thermophilus hb8]] | ||
| + | [[Category: Gorecka, K M.]] | ||
| + | [[Category: Komorowska, W.]] | ||
| + | [[Category: Nowotny, M.]] | ||
| + | [[Category: Dna]] | ||
| + | [[Category: Hydrolase-dna complex]] | ||
| + | [[Category: Nuclease]] | ||
| + | [[Category: Rnase h fold]] | ||
Revision as of 11:01, 4 September 2013
T. thermophilus RuvC in complex with Holliday junction substrate
Function
[RUVC_THET8] Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity).
About this Structure
4ld0 is a 5 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.
