4b81
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
{{STRUCTURE_4b81| PDB=4b81 | SCENE= }} | {{STRUCTURE_4b81| PDB=4b81 | SCENE= }} | ||
===Mus musculus Acetylcholinesterase in complex with 1-(4-Chloro-phenyl)- N-(2-diethylamino-ethyl)-methanesulfonamide=== | ===Mus musculus Acetylcholinesterase in complex with 1-(4-Chloro-phenyl)- N-(2-diethylamino-ethyl)-methanesulfonamide=== | ||
| + | {{ABSTRACT_PUBMED_23984975}} | ||
==Function== | ==Function== | ||
| Line 7: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
[[4b81]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B81 OCA]. | [[4b81]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B81 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023984975</ref><references group="xtra"/><references/> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
Revision as of 04:16, 12 September 2013
Contents |
Mus musculus Acetylcholinesterase in complex with 1-(4-Chloro-phenyl)- N-(2-diethylamino-ethyl)-methanesulfonamide
Template:ABSTRACT PUBMED 23984975
Function
[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
About this Structure
4b81 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekstrom FJ, Linusson A. Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J Med Chem. 2013 Aug 28. PMID:23984975 doi:10.1021/jm400990p
