4h9g

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-	'''Unreleased structure'''	+	{{STRUCTURE_4h9g| PDB=4h9g | SCENE= }}
		+	===Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket===
		+	{{ABSTRACT_PUBMED_23989163}}
-	The entry 4h9g is ON HOLD	+	==Function==
		+	[[http://www.uniprot.org/uniprot/EFTU1_THETH EFTU1_THETH]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
-	Authors: Groftehauge, M.K., Therkelsen, M., Taaning, R.H., Skrydstrup, T., Morth, J.P., Nissen, P.	+	==About this Structure==
		+	[[4h9g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H9G OCA].
-	Description: Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket	+	==Reference==
		+	<ref group="xtra">PMID:023989163</ref><references group="xtra"/><references/>
		+	[[Category: Protein-synthesizing GTPase]]
		+	[[Category: Thermus thermophilus]]
		+	[[Category: Groftehauge, M K.]]
		+	[[Category: Morth, J P.]]
		+	[[Category: Nissen, P.]]
		+	[[Category: Skrydstrup, T.]]
		+	[[Category: Taaning, R H.]]
		+	[[Category: Therkelsen, M.]]
		+	[[Category: Gtp binding]]
		+	[[Category: Gtpase]]
		+	[[Category: P-loop]]
		+	[[Category: Ribosome binding]]
		+	[[Category: Translation]]
		+	[[Category: Trna binding]]

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Revision as of 05:17, 12 September 2013

Template:STRUCTURE 4h9g

Contents 1 Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket 2 Function 3 About this Structure 4 Reference

Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket

Template:ABSTRACT PUBMED 23989163

Function

[EFTU1_THETH] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

About this Structure

4h9g is a 1 chain structure with sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

• Groftehauge MK, Therkelsen MO, Taaning R, Skrydstrup T, Morth JP, Nissen P. Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1060-5. doi: , 10.1107/S1744309113018551. Epub 2013 Aug 19. PMID:23989163 doi:10.1107/S1744309113018551