4jgw

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'''Unreleased structure'''
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{{STRUCTURE_4jgw| PDB=4jgw | SCENE= }}
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===The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf===
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{{ABSTRACT_PUBMED_23891840}}
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The entry 4jgw is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/RGL2_MOUSE RGL2_MOUSE]] Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
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Authors: Rehmann, H., Popovic, M., Jakobi, A.
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==About this Structure==
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[[4jgw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JGW OCA].
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Description: The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf
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==Reference==
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<ref group="xtra">PMID:023891840</ref><references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Jakobi, A J.]]
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[[Category: Popovic, M.]]
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[[Category: Rehmann, H.]]
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[[Category: Cdc25-homology domain]]
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[[Category: Guanine nucleotide exchange factor]]
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[[Category: Rem-domain]]
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[[Category: Sh3 domain binding]]
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[[Category: Signaling protein]]
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[[Category: Small g-protein binding]]

Revision as of 05:24, 12 September 2013

Template:STRUCTURE 4jgw

Contents

The conformation of a docking site for SH3 domains is pre-selected in the Guanine Nucleotide Exchange Factor Rlf

Template:ABSTRACT PUBMED 23891840

Function

[RGL2_MOUSE] Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.

About this Structure

4jgw is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Popovic M, Jakobi AJ, Rensen-de Leeuw M, Rehmann H. The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation. J Struct Biol. 2013 Sep;183(3):312-9. doi: 10.1016/j.jsb.2013.07.009. Epub 2013, Jul 24. PMID:23891840 doi:10.1016/j.jsb.2013.07.009

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OCA

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