4btl

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-	'''Unreleased structure'''	+	{{STRUCTURE_4btl| PDB=4btl | SCENE= }}
		+	===Aromatic interactions in acetylcholinesterase-inhibitor complexes===
		+	{{ABSTRACT_PUBMED_23984975}}
-	The entry 4btl is ON HOLD until Paper Publication	+	==Function==
		+	[[http://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
-	Authors: Andersson, C.D., Forsgren, N., Akfur, C., Allgardsson, A., Qian, W., Engdahl, C., Berg, L., Ekstrom, F., Linusson, A.	+	==About this Structure==
		+	[[4btl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BTL OCA].
-	Description: Aromatic interactions in acetylcholinesterase-inhibitor complexes	+	==Reference==
		+	<ref group="xtra">PMID:023984975</ref><references group="xtra"/><references/>
		+	[[Category: Acetylcholinesterase]]
		+	[[Category: Mus musculus]]
		+	[[Category: Akfur, C.]]
		+	[[Category: Allgardsson, A.]]
		+	[[Category: Andersson, C D.]]
		+	[[Category: Berg, L.]]
		+	[[Category: Ekstrom, F.]]
		+	[[Category: Engdahl, C.]]
		+	[[Category: Forsgren, N.]]
		+	[[Category: Linusson, A.]]
		+	[[Category: Qian, W.]]
		+	[[Category: Acetylcholinesterase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inhibitor]]

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Revision as of 05:25, 12 September 2013

Template:STRUCTURE 4btl

Contents 1 Aromatic interactions in acetylcholinesterase-inhibitor complexes 2 Function 3 About this Structure 4 Reference

Aromatic interactions in acetylcholinesterase-inhibitor complexes

Template:ABSTRACT PUBMED 23984975

Function

[ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.

About this Structure

4btl is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

• Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian W, Ekstrom FJ, Linusson A. Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J Med Chem. 2013 Aug 28. PMID:23984975 doi:10.1021/jm400990p