4c2s

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m (Protected "4c2s" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4c2s| PDB=4c2s | SCENE= }}
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===Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor===
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The entry 4c2s is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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Authors: Wedge, J.T., Palcic, M., Henriksen, A.
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==About this Structure==
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[[4c2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C2S OCA].
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Description: Crystal structure of the fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor
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[[Category: Homo sapiens]]
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[[Category: Henriksen, A.]]
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[[Category: Palcic, M.]]
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[[Category: Wedge, J T.]]
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[[Category: Abo]]
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[[Category: Blood group antigen]]
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[[Category: Glycosylation]]
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[[Category: Gta]]
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[[Category: Transferase]]

Revision as of 05:29, 12 September 2013

Template:STRUCTURE 4c2s

Crystal structure of the fucosylgalactoside alpha N- acetylgalactosaminyltransferase (GTA P156L mutant) in complex with UDP and deoxy-H-antigen acceptor

Function

[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

About this Structure

4c2s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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OCA

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