4kc2

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'''Unreleased structure'''
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{{STRUCTURE_4kc2| PDB=4kc2 | SCENE= }}
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===Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate===
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The entry 4kc2 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
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Authors: Cuesta-Seijo, J.A., Wang, S., Lafont, D., Vidal, S., Palcic, M.M.
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==About this Structure==
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[[4kc2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KC2 OCA].
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Description:
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[[Category: Homo sapiens]]
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[[Category: Cuesta-Seijo, J A.]]
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[[Category: Lafont, D.]]
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[[Category: Palcic, M M.]]
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[[Category: Vidal, S.]]
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[[Category: Wang, S.]]
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[[Category: Blood group protein]]
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[[Category: Fuc-gal]]
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[[Category: Glycosyltransferase]]
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[[Category: Gta superfamily]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Udp-gal]]
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[[Category: Udp-galnac]]

Revision as of 05:32, 12 September 2013

Template:STRUCTURE 4kc2

Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate

Function

[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

About this Structure

4kc2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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OCA

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