4afn
From Proteopedia
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{{STRUCTURE_4afn| PDB=4afn | SCENE= }} | {{STRUCTURE_4afn| PDB=4afn | SCENE= }} | ||
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===Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa at 2.3A resolution=== | ===Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa at 2.3A resolution=== | ||
| + | {{ABSTRACT_PUBMED_24015914}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/FABG_PSEAE FABG_PSEAE]] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[4afn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFN OCA]. | [[4afn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFN OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:024015914</ref><references group="xtra"/><references/> | ||
[[Category: Pseudomonas aeruginosa pao1]] | [[Category: Pseudomonas aeruginosa pao1]] | ||
[[Category: Cukier, C D.]] | [[Category: Cukier, C D.]] | ||
Revision as of 02:38, 20 September 2013
Contents |
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa at 2.3A resolution
Template:ABSTRACT PUBMED 24015914
Function
[FABG_PSEAE] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis (By similarity).
About this Structure
4afn is a 4 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Cukier CD, Hope AG, Elamin AA, Moynie L, Schnell R, Schach S, Kneuper H, Singh M, Naismith JH, Lindqvist Y, Gray DW, Schneider G. Discovery of an allosteric inhibitor binding site in 3-oxo-acyl-ACP reductase from Pseudomonas aeruginosa. ACS Chem Biol. 2013 Sep 9. PMID:24015914 doi:10.1021/cb4005063
