1syl
From Proteopedia
(Difference between revisions)
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{{STRUCTURE_1syl| PDB=1syl | SCENE= }} | {{STRUCTURE_1syl| PDB=1syl | SCENE= }} | ||
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===Crystal structure of inactive mutant dUTPase complexed with substrate dUTP=== | ===Crystal structure of inactive mutant dUTPase complexed with substrate dUTP=== | ||
| + | {{ABSTRACT_PUBMED_15208312}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DUT_ECOLI DUT_ECOLI]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116] | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:015208312</ref>< | + | <ref group="xtra">PMID:015208312</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: DUTP diphosphatase]] | [[Category: DUTP diphosphatase]] | ||
Revision as of 02:42, 20 September 2013
Contents |
Crystal structure of inactive mutant dUTPase complexed with substrate dUTP
Template:ABSTRACT PUBMED 15208312
Function
[DUT_ECOLI] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116]
About this Structure
1syl is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Barabas O, Pongracz V, Kovari J, Wilmanns M, Vertessy BG. Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase. J Biol Chem. 2004 Oct 8;279(41):42907-15. Epub 2004 Jun 17. PMID:15208312 doi:10.1074/jbc.M406135200
