3u8j
From Proteopedia
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===Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3531 (1-(pyridin-3-yl)-1,4-diazepane)=== | ===Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3531 (1-(pyridin-3-yl)-1,4-diazepane)=== | ||
| + | {{ABSTRACT_PUBMED_22170047}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission. | ||
==About this Structure== | ==About this Structure== | ||
[[3u8j]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U8J OCA]. | [[3u8j]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U8J OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022170047</ref><references group="xtra"/><references/> | ||
[[Category: Lymnaea stagnalis]] | [[Category: Lymnaea stagnalis]] | ||
[[Category: Ahring, P K.]] | [[Category: Ahring, P K.]] | ||
Revision as of 02:43, 20 September 2013
Contents |
Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3531 (1-(pyridin-3-yl)-1,4-diazepane)
Template:ABSTRACT PUBMED 22170047
Function
[ACHP_LYMST] Binds to acetylcholine. Modulates neuronal synaptic transmission.
About this Structure
3u8j is a 10 chain structure with sequence from Lymnaea stagnalis. Full crystallographic information is available from OCA.
Reference
- Rohde LA, Ahring PK, Jensen ML, Nielsen EO, Peters D, Helgstrand C, Krintel C, Harpsoe K, Gajhede M, Kastrup JS, Balle T. Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha4beta2 receptors: unique role of halogen bonding revealed. J Biol Chem. 2012 Feb 3;287(6):4248-59. Epub 2011 Dec 13. PMID:22170047 doi:10.1074/jbc.M111.292243
Categories: Lymnaea stagnalis | Ahring, P K. | Balle, T. | Gajhede, M. | Harpsoe, K. | Helgstrand, C. | Jensen, M L. | Kastrup, J S. | Krintel, C. | Nielsen, E O. | Peters, D. | Rohde, L A.H. | Acetylcholine | Acetylcholine-binding protein | Acetylcholine-binding protein-agonist complex | Agonist | Ligand-bindig domain | Lymnaea stagnali
